Abstract

Opinion

Why is Pain not Characteristic of Inflammation of the Lung Tissue?

Igor Klepikov*

Published: 07 March, 2024 | Volume 9 - Issue 1 | Pages: 005-007

The article presents materials that make it possible to understand the reason for the absence of one of the classic signs of inflammatory processes in patients with acute pneumonia. The peculiarities of the functional significance of the lungs for the body are the reason that in the case of inflammation in the tissues of the organ, nature has provided for the presence of a more important adaptive mechanism instead of pain as a signal sign. Understanding the causes of the absence of pain in pneumonia in the initial period, which is most responsible for timely and effective care for these patients, allows us to look at the pathogenesis of the disease from a new point of view, which is of fundamental importance for the correction and selection of pathogenetic means of care.

Read Full Article HTML DOI: 10.29328/journal.jcicm.1001046 Cite this Article Read Full Article PDF

Keywords:

Acute pneumonia; Pain; Pulmonary vascular baroreceptors; Discharge reflex; Pathogenesis of pulmonary inflammation

References

  1. Chandrasoma P, Taylor CR. "Part A. "General Pathology", Section II. "The Host Response to Injury", Chapter 3. "The Acute Inflammatory Response", sub-section "Cardinal Clinical Signs". Concise Pathology (3rd ed.). McGraw-Hill.
  2. Schwiegk H. Der Lungenentlastungsreflex. Pflügers Arch Ges Physiol. 1935; 236: 206-219.
  3. Klepikov I. The Didactics of Acute Lung Inflammation. Cambridge Scholars Publishing. 2022; 320.
  4. Thillai M, Patvardhan C, Swietlik EM, McLellan T, De Backer J, Lanclus M, De Backer W, Ruggiero A. Functional respiratory imaging identifies redistribution of pulmonary blood flow in patients with COVID-19. Thorax. 2021 Feb;76(2):182-184. doi: 10.1136/thoraxjnl-2020-215395. Epub 2020 Aug 28. PMID: 32859733.
  5. Dierckx W, De Backer W, Lins M, De Meyer Y, Ides K, Vandevenne J, De Backer J, Franck E, Lavon BR, Lanclus M, Thillai M. CT-derived measurements of pulmonary blood volume in small vessels and the need for supplemental oxygen in COVID-19 patients. J Appl Physiol (1985). 2022 Dec 1;133(6):1295-1299. doi: 10.1152/japplphysiol.00458.2022. Epub 2022 Oct 21. PMID: 36269576; PMCID: PMC9722246.

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