A Behçet’s Disease Patient with Postoperative Perivalvular Leakage: A Case Report

Main Article Content

Xinyu Pu
Liya Wei

Abstract

Behcet’s disease, a rare chronic recurrent vasculitis, affects various arteries and veins. A young female with aortic valve - involved Behcet’s disease had aortic valve replacement. Paravalvular leakage then occurred and quickly progressed to left ventricular wall dissection, leading to aortic valve root replacement. Current routine follow - up shows no significant issues. This article aims to boost clinicians’ awareness of Behcet’s disease for timely diagnosis and treatment of more patients.

Article Details

Pu, X., & Wei, L. (2026). A Behçet’s Disease Patient with Postoperative Perivalvular Leakage: A Case Report. Journal of Clinical Intensive Care and Medicine, 25–28. https://doi.org/10.29328/journal.jcicm.1001060
Case Reports

Copyright (c) 2026 Pu X, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Lavalle S, Caruso S, Foti R, Gagliano C, Cocuzza S, La Via L, et al. Behçet’s Disease, Pathogenesis, Clinical Features, and Treatment Approaches: A Comprehensive Review. Medicina (Kaunas) 2024;60:562. Available from: https://doi.org/10.3390/medicina60040562.

Bergamo S, di Meo N, Stinco G, Bonin S, Trevisini S, Trevisan G. Adamantiades-Behçet Disease at the Beginning of the Silk Route: North-East Italian Experience. Acta Dermatovenerol Croat 2017;25:295–7.

Yazici Y, Hatemi G, Bodaghi B, Cheon JH, Suzuki N, Ambrose N, et al. Behçet syndrome. Nat Rev Dis Primers 2021;7:67. Available from: https://doi.org/10.1038/s41572-021-00301-1.

Hassan F, Jeries H, Naffaa ME. Challenges in the Timely Diagnosis of Behcet’s Disease. Life (Basel) 2023;13:1157. Available from: https://doi.org/10.3390/life13051157.

International Team for the Revision of the International Criteria for Behçet’s Disease (ITR-ICBD). The International Criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol 2014;28:338–47. Available from: https://doi.org/10.1111/jdv.12107.

Zhang Y, Yang K, Meng X, Tian T, Fan P, Zhang H, et al. Cardiac Valve Involvement in Takayasu Arteritis Is Common: A Retrospective Study of 1,069 Patients Over 25 Years. The American Journal of the Medical Sciences 2018;356:357–64. Available from: https://doi.org/10.1016/j.amjms.2018.06.021.

Barra L, Kanji T, Malette J, Pagnoux C. Imaging modalities for the diagnosis and disease activity assessment of Takayasu’s arteritis: A systematic review and meta-analysis. Autoimmunity Reviews 2018;17:175–87. Available from: https://doi.org/10.1016/j.autrev.2017.11.021.

Choi SJ, Koo HJ, Yang DH, Kang JW, Oh JS, Hong S, et al. Comparison of Clinical, Angiographic Features and Outcome in Takayasu’s Arteritis and Behçet’s Disease With Arterial Involvement. J Rheum Dis 2020;27:100. Available from: https://doi.org/10.4078/jrd.2020.27.2.100.

Fei Y, Li X, Lin S, Song X, Wu Q, Zhu Y, et al. Major vascular involvement in Behçet’s disease: a retrospective study of 796 patients. Clin Rheumatol 2013;32:845–52. Available from: https://doi.org/10.1007/s10067-013-2205-7.

Kageyama S, Ohashi T, Tadakoshi M, Kamikawa Y, Kojima A, Yamauchi H, et al. [Four Times Aortic Valve Replacement for Recurrent Aortic Annulus Destruction Due to Behçet’s Disease: Report of a Case]. Kyobu Geka 2021;74:681–5.

Jung Y, Ahn BH, Lee KS, Jeong IS, Kim KH, Na KJ, et al. A novel solution to prosthetic valve dehiscence after aortic valve surgery in Behçet’s disease. Interact Cardiovasc Thorac Surg 2017;24:342–7. Available from: https://doi.org/10.1093/icvts/ivw361.

Geri G, Wechsler B, Thi Huong DL, Isnard R, Piette J-C, Amoura Z, et al. Spectrum of Cardiac Lesions in Behçet Disease: A Series of 52 Patients and Review of the Literature. Medicine 2012;91:25–34. Available from: https://doi.org/10.1097/MD.0b013e3182428f49.